Important Drug Interactions with SSRI’s 9/28/2017

Selective serotonin reuptake inhibitors (SSRIs) are commonly used psychotropic medications to treat depression and anxiety. It is important to be aware of common drug interactions between them and other medications, especially because some SSRIs are competitive inhibitors of a variety of cytochrome P450 liver enzymes. Therefore, they can dramatically increase the blood levels of medications […]

Complementary and/or Alternative Medicine Concerns 10/5/2017

Many people are interested in using complementary and/or alternative medicine (CAM) when they are dealing with physical or mental health concerns. This is sometimes because they are worried about side effects from traditional medical treatments. Sometimes it is because they are not seeing the relief they expected from the traditional treatment prescribed by their medical […]

Supported vs. Unsupported Off Label Prescribing 10/12/2017

Off-label prescribing is a central and common source of treatment throughout medicine, particularly psychiatry. Lack of FDA indication does not equate to lack of evidence. It is therefore important to distinguish between supported and unsupported off-label prescribing practices. Supported off-label prescribing is the use of medications for a non-FDA-approved indication with clinical literature to support […]

Positive Mental Health: A Better Outcome Measure for Remission? 10/26/2017

Symptom remission has been traditionally used as the outcome measure for remission in mental health disorders. This is how remission is defined in clinical trials. But is that what patients actually perceive as remission or what they want from treatment? When this has been assessed further, patients indicate what they are looking for with remission […]

Prazosin: Effective or Not? 2/22/2018

Prazosin (brand name = Minipress) is an alpha agonist medication that has long been used for hypertension and benign prostatic hyperplasia (BPH). It has anecdotally been found to be helpful for nightmares and sleep disturbance in patients with Post Traumatic Stress Disorder (PTSD) and has become increasingly used in veterans with PTSD. The starting dose […]

Non-Suicidal Self Injury 11/2/2017

Also known as self-injury and self-harm, nonsuicidal self-injury (NSSI) refers to the deliberate and direct alteration or destruction of healthy body tissue without suicidal intent. This can range from skin cutting or burning to amputation of body parts. There can also be a significant cultural component to the self-injury. While NSSI acts are done without […]

Learning From Behavioral Health Screening Tools 11/9/2017

Patients, pediatric and adult commonly present to primary care offices with symptoms and concerns related to their mental health or substance use problems. Sometimes they come in with that as part of their chief complaint, but often a PCP will have a concern that a behavioral health issue is present, either based on the physical […]

Treatment of Insomnia in Anxiety Disorders 11/16/2017

Insomnia is a common symptom in anxiety disorders, in fact it is a criteria for several DSM-IV Anxiety Disorders. It is important to inquire about sleep disturbance as part of the assessment for anxiety disorders, especially because there is clear evidence that the presence of insomnia in anxiety disorders is associated with increased morbidity. It […]